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The effect of trifluralin on the growth and development of cotton plants in low-organic-matter soils from the northern Negev of Israel was studied. Trifluralin exhibited linear sorption isotherms on these soils. Trifluralin and dinitramine losses from soils under varying moisture regimes and application practices were determined in open systems. The data were fitted to both first-order and biexponential kinetic equations. In about 50% of cases the biexponential kinetic model provided a better fit to the data, but no relationship could be found between the model parameters and environmental or soil properties. Losses were generally greater at field capacity than at 50% field capacity, and at 27-degrees-C than at 15-degrees-C, and in soils with a lower organic matter content. The trifluralin application rate was negatively correlated with vegetative growth parameters of cotton, but the correlation became weaker with increasing soil organic carbon content. Trifluralin delayed boll production in coarse textured soils, the longest delay occurring at higher application rates. It is concluded that in light soils that contain very little organic matter, trifluralin rates must be maintained at the minimum level required for adequate weed control to prevent damage to crops.