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Shells of Chaenaxis tuba Pilsbry & Ferriss, 1906 (Pupillidae) were recovered from five radiocarbon-dated packrat (Neotoma) middens from the Waterman Mountains, northeastern Sonoran Desert, Pima County, Arizona. Associated plant macrofossils indicate that C. tuba has been present in rocky limestone habitats for 11,470 yr as the local vegetation shifted from a pinyon-juniper woodland in the late Wisconsin glacial to a postglacial juniper woodland/chaparral in the early Holocene (9920 yr B.P.) to a mesic Sonoran desertscrub in the middle Holocene (8910 to 4845 yr B.P.) to a modern desertscrub in the late Holocene (1320 yr B.P.). Chaenaxis tuba persisted in the community in spite of the climatic and vegetational changes within the local habitat.