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OASIS/CREB3L1 is epigenetically silenced in human bladder cancer facilitating tumor cell spreading and migration in vitro 期刊论文
发表期刊: EPIGENETICS. 出版年: 2014, 卷号: 9, 期号: 12, 页码: 1626-1640
作者:  Rose, Michael;  Schubert, Claudia;  Dierichs, Laura;  Gaisa, Nadine T.;  Heer, Matthias;  Heidenreich, Axel;  Knuechel, Ruth;  Dahl, Edgar
收藏  |  浏览/下载：17/0  |  提交时间：2019/11/29
bladder cancer  HTRA3  OASIS  CREB3L1  promoter methylation  tumor cell migration  tumor suppressor gene  ATCC  American Type Culture Collection  BMP-2  bone morphogenetic protein 2  CA  California  cDNA  copy number desoxyribonucleic acid  CIS  Carcinoma in situ  CREB3L1  element binding protein 3-like 1  DAB  3-3 diaminobenzidine  DAC  5-aza-2-deoxycytidine  DNA  desoxyribonucleic acid  EK  ethics committee  ER  endoplasmic reticulum  FC  fold change  FFPE  formalin fixed paraffin embedded  G1  well differentiated  G2  moderately differentiated  G3  poorly differentiated  GAPDH  glyceraldehyde 3-phosphate dehydrogenase  HCV  Hepatitis C virus  HPV  human papilloma virus  HTRA (1-4)  high-temperature requirement factor A (1-4)  IQR  interquartile range  IRS  immunoreactive score  LMU  Ludwig-Maximilians-University  M  methylated  MIBC  muscle invasive bladder cancer  mRNA  messenger ribo nucleic acid  MSP  methylation specific PCR  n  number  NMIBC  non-muscle invasive bladder cancer  ns  not significant  NU  normal urothelium  OASIS  old astrocyte specifically-induced substance  PCR  polymerase chain reaction  pTa  papillary non-invasive tumors  RIP  regulated intramembrane proteolysis  RWTH  Rheinisch Westfalisch Technische Hochschule  s  e  m  standard error of the margin  SP1  site 1 protease  SP2  site 2 protease  TCGA  The Cancer Genome Atlas  TGF-  transforming growth factor beta  TSA  trichostatin A  TSS  transcription start site  U  unmethylated  UC  urothelial cell cancer  UPR  unfold protein response  USA  United States of America  WHO  World Health Organization  WI  Wisconsin  
High Throughput Screening of High-Affinity Ligands for Proteins with Anion-Binding Sites using Desorption Electrospray Ionization (DESI) Mass Spectrometry 期刊论文
发表期刊: JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY. 出版年: 2014, 卷号: 25, 期号: 3, 页码: 454-463
作者:  Lu, Xin;  Ning, Baoming;  He, Dacheng;  Huang, Lingyun;  Yue, Xiangjun;  Zhang, Qiming;  Huang, Haiwei;  Liu, Yang;  He, Lan;  Ouyang, Jin
收藏  |  浏览/下载：12/0  |  提交时间：2019/11/29
High throughput screening  Desorption electrospray ionization  Specific binding  Anion-binding site  Coulomb explosion induced dissociation  Anionic region inhibited dissociation