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A familial syndrome of hypothalamic hamartomas, polydactyly, and SMO mutations: a clinical report of 2 cases 期刊论文
发表期刊: JOURNAL OF NEUROSURGERY-PEDIATRICS. 出版年: 2019, 卷号: 23, 期号: 1, 页码: 98-103
作者:  Rubino, Sebastian;  Qian, Jiang;  Pinheiro-Neto, Carlos D.;  Kenning, Tyler J.;  Adamo, Matthew A.
收藏  |  浏览/下载:21/0  |  提交时间:2019/11/29
hypothalamic hamartoma  Smoothened gene  SMO  Chiari malformation type I  gelastic/dacrystic seizures  oncology  
Cyclopamine did not affect mouse oocyte maturation in vitro but decreased early embryonic development 期刊论文
发表期刊: ANIMAL SCIENCE JOURNAL. 出版年: 2014, 卷号: 85, 期号: 9, 页码: 840-847
作者:  Liu, Yang;  Wei, Zhuying;  Huang, Yafei;  Bai, Chunling;  Zan, Linsen;  Li, Guangpeng
收藏  |  浏览/下载:25/0  |  提交时间:2019/11/29
embryo  gli1  patched 1  smoothened  sonic hedgehog  
TAK-441, a novel investigational smoothened antagonist, delays castration-resistant progression in prostate cancer by disrupting paracrine hedgehog signaling 期刊论文
发表期刊: INTERNATIONAL JOURNAL OF CANCER. 出版年: 2013, 卷号: 133, 期号: 8, 页码: 1955-1966
作者:  Ibuki, Naokazu;  Ghaffari, Mazyar;  Pandey, Mitali;  Iu, Irene;  Fazli, Ladan;  Kashiwagi, Masahide;  Tojo, Hideaki;  Nakanishi, Osamu;  Gleave, Martin E.;  Cox, Michael E.
收藏  |  浏览/下载:22/0  |  提交时间:2019/11/29
prostate cancer  hedgehog signaling  smoothened  small molecule inhibitor  
Hedgehog pathway as a drug target: Smoothened inhibitors in development 期刊论文
发表期刊: ONCOTARGETS AND THERAPY. 出版年: 2012, 卷号: 5, 页码: 47-58
作者:  Lin, Tara L.;  Matsui, William
收藏  |  浏览/下载:11/0  |  提交时间:2019/11/29
hedgehog pathway  Smoothened inhibitors  cancer stem cells  
Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways 期刊论文
发表期刊: CELL CYCLE. 出版年: 2010, 卷号: 9, 期号: 3, 页码: 570-579
作者:  Chinchilla, Pilar;  Xiao, Liqing;  Kazanietz, Marcelo G.;  Riobo, Natalia A.
收藏  |  浏览/下载:14/0  |  提交时间:2019/11/29
hedgehog  smoothened  endothelial cells  G proteins  Rho  patched  
Expression of Patched-1 and Smoothened in Testicular Meiotic and Post-Meiotic Cells 期刊论文
发表期刊: MICROSCOPY RESEARCH AND TECHNIQUE. 出版年: 2009, 卷号: 72, 期号: 11, 页码: 809-815
作者:  Morales, Carlos R.;  Fox, Andrew;  El-Alfy, Mohamed;  Ni, Xiaoyan;  Argraves, W. Scott
收藏  |  浏览/下载:38/0  |  提交时间:2019/11/28
patched-1  smoothened  desert hedgehog  development  testis  
Hedgehog signaling in the normal and diseased pancreas 期刊论文
发表期刊: PANCREAS. 出版年: 2006, 卷号: 32, 期号: 2, 页码: 119-129
作者:  Kayed, Hany;  Kleeff, Joerg;  Osman, Tarek;  Keleg, Shereen;  Buechler, Markus W.;  Friess, Helmut
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/28
patched  smoothened  Indian hedgehog  sonic hedgehog  pancreatic cancer  chronic pancreatitis  
The Hedgehog signaling network 期刊论文
发表期刊: AMERICAN JOURNAL OF MEDICAL GENETICS PART A. 出版年: 2003, 期号: 1, 页码: 5-28
作者:  Cohen, MM
收藏  |  浏览/下载:15/0  |  提交时间:2019/11/28
Sonic Hedgehog  Indian Hedgehog  Desert Hedgehog  Multimeric Hedgehog  cholesterol metabolism  palmitoylation  Dispatched  Hip  GAS1  Tout-velu  EXT gene family  Patched  Patched 2  TRC8  sterol sensing domain  Megalin  Rab23  Smoothened  Cubitus interruptus  Gli gene family  Costal 2  Fused  Suppressor of Fused  PKA  Slimb  SAP18  GSK3  CK1  CBP  Decapentaplegic  BMPs  Wingless  Wnt gene family  holoprosencephaly  nevoid basal cell carcinoma syndrome  Pallister-Hall syndrome  Greig cephalopolysyndactyly Rubinstein-Taybi  syndrome  multiple exostoses  VACTERL  
The Hedgehog signaling network 会议论文
会议名称: Bryan D Hall Meeting 2003. 会议地点: LOS ANGELES, CALIFORNIA. 会议日期: MAR, 2003
作者:  Cohen, MM
收藏  |  浏览/下载:13/0  |  提交时间:2019/12/07
Sonic Hedgehog  Indian Hedgehog  Desert Hedgehog  Multimeric Hedgehog  cholesterol metabolism  palmitoylation  Dispatched  Hip  GAS1  Tout-velu  EXT gene family  Patched  Patched 2  TRC8  sterol sensing domain  Megalin  Rab23  Smoothened  Cubitus interruptus  Gli gene family  Costal 2  Fused  Suppressor of Fused  PKA  Slimb  SAP18  GSK3  CK1  CBP  Decapentaplegic  BMPs  Wingless  Wnt gene family  holoprosencephaly  nevoid basal cell carcinoma syndrome  Pallister-Hall syndrome  Greig cephalopolysyndactyly Rubinstein-Taybi  syndrome  multiple exostoses  VACTERL  
Clinical aspects of disrupted Hedgehog signaling (review) 期刊论文
发表期刊: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 出版年: 2001, 卷号: 8, 期号: 4, 页码: 445-452
作者:  Oldak, M;  Grzela, T;  Lazarczyk, M;  Malejczyk, J;  Skopinski, P
收藏  |  浏览/下载:33/0  |  提交时间:2019/11/28
Hedgehog signaling pathway  patched (PTCH)  smoothened (SMOH)  GLI  carcinoma  malformation syndromes