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Integrated approach to testing and assessment for predicting rodent genotoxic carcinogenicity 期刊论文
发表期刊: JOURNAL OF APPLIED TOXICOLOGY. 出版年: 2016, 卷号: 36, 期号: 12, 页码: 1536-1550
作者:  Petkov, Petko I.;  Schultz, Terry W.;  Donner, E. Maria;  Honma, Masamitsu;  Morita, Takeshi;  Hamada, Shuichi;  Wakata, Akihiro;  Mishima, Masayuki;  Maniwa, Jiro;  Todorov, Milen;  Kaloyanova, Elena;  Kotov, Stefan;  Mekenyan, Ovanes G.
收藏  |  浏览/下载:19/0  |  提交时间:2019/11/29
carcinogenicity  IATA  genotoxicity  OECD Toolbox  TIMES  
Towards AOP application - Implementation of an integrated approach to testing and assessment (IATA) into a pipeline tool for skin sensitization 期刊论文
发表期刊: REGULATORY TOXICOLOGY AND PHARMACOLOGY. 出版年: 2014, 卷号: 69, 期号: 3, 页码: 529-545
作者:  Patlewicz, Grace;  Kuseva, Chanita;  Kesoya, Antonia;  Popova, Loanna;  Zhechev, Teodor;  Pavlov, Todor;  Roberts, David W.;  Mekenyan, Ovanes
收藏  |  浏览/下载:20/0  |  提交时间:2019/11/29
Adverse Outcome Pathway (AOP)  Integrated Approaches to Testing and  Assessment (IATA)  Expert systems  TIMES-SS  (Q)SAR  Read-across  
A Mechanistic Approach to Modeling Respiratory Sensitization 期刊论文
发表期刊: CHEMICAL RESEARCH IN TOXICOLOGY. 出版年: 2014, 卷号: 27, 期号: 2, 页码: 219-239
作者:  Mekenyan, Ovanes;  Patlewicz, Grace;  Kuseva, Chanita;  Popova, Ioanna;  Mehmed, Aycel;  Kotov, Stefan;  Zhechev, Teodor;  Pavlov, Todor;  Temelkov, Stanislav;  Roberts, David W.
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/29
Investigating the Relationship between in Vitro-in Vivo Genotoxicity: Derivation of Mechanistic QSAR Models for in Vivo Liver Genotoxicity and in Vivo Bone Marrow Micronucleus Formation Which Encompass Metabolism 期刊论文
发表期刊: CHEMICAL RESEARCH IN TOXICOLOGY. 出版年: 2012, 卷号: 25, 期号: 2, 页码: 277-296
作者:  Mekenyan, Ovanes G.;  Petkov, Petko I.;  Kotov, Stefan V.;  Stoeva, Stoyanka;  Kamenska, Verginia B.;  Dimitrov, Sabcho D.;  Honma, Masamitsu;  Hayashi, Makoto;  Benigni, Romualdo;  Donner, E. Maria;  Patlewicz, Grace
收藏  |  浏览/下载:17/0  |  提交时间:2019/11/29
Representation of chemical information in OASIS centralized 3D database for existing chemicals 期刊论文
发表期刊: JOURNAL OF CHEMICAL INFORMATION AND MODELING. 出版年: 2006, 卷号: 46, 期号: 6, 页码: 2537-2551
作者:  Nikolov, Nikolai;  Grancharov, Vanio;  Stoyanova, Galya;  Pavlov, Todor;  Mekenyan, Ovanes
收藏  |  浏览/下载:12/0  |  提交时间:2019/11/28