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The Role of Structural Flexibility and Stability in the Interaction of Serine Proteases with their Inhibitors 期刊论文
发表期刊: CURRENT PROTEIN & PEPTIDE SCIENCE. 出版年: 2015, 卷号: 16, 期号: 6, 页码: 521-531
作者:  Graf, Laszlo;  Molnar, Tamas;  Kardos, Jozsef;  Gaspari, Zoltan;  Katona, Gergely
收藏  |  浏览/下载:15/0  |  提交时间:2019/11/29
Canonical inhibitors  flexibility  protein-protein interactions  serine proteases  serpins  stability  
CoNSEnsX: an ensemble view of protein structures and NMR-derived experimental data 期刊论文
发表期刊: BMC STRUCTURAL BIOLOGY. 出版年: 2010, 卷号: 10
作者:  Angyan, Annamaria F.;  Szappanos, Balazs;  Perczel, Andras;  Gaspari, Zoltan
收藏  |  浏览/下载:4/0  |  提交时间:2019/11/29
Reconciling the lock-and-key and dynamic views of canonical serine protease inhibitor action 期刊论文
发表期刊: FEBS LETTERS. 出版年: 2010, 卷号: 584, 期号: 1, 页码: 203-206
作者:  Gaspari, Zoltan;  Varnai, Peter;  Szappanos, Balazs;  Perczel, Andras
收藏  |  浏览/下载:17/0  |  提交时间:2019/11/29
Canonical serine protease inhibitor  Nanosecond-timescale conformer selection  Protease binding  Internal dynamics  Dynamic conformational ensemble  Population shift  
When the surface tells what lies beneath: Combinatorial phage-display mutagenesis reveals complex networks of surface-core interactions in the pacifastin protease inhibitor family 期刊论文
发表期刊: JOURNAL OF MOLECULAR BIOLOGY. 出版年: 2007, 卷号: 370, 期号: 1, 页码: 63-79
作者:  Szenthe, Borbala;  Patthy, Andras;  Gaspari, Zoltan;  Kekesi, Adrienna Katalin;  Graf, Laszlo;  Pal, Gabor
收藏  |  浏览/下载:14/0  |  提交时间:2019/11/28
phage-display  protease inhibitor  pacifastin  taxon-specificity  core-surface interaction network  
Structure, dynamics and rational design of small chymotrypsin inhibitors 会议论文
会议名称: 3rd International Peptide Symposium/28th European Peptide Symposium. 会议地点: Prague, CZECH REPUBLIC. 会议日期: SEP 05-10, 2004
作者:  Gaspari, Zoltan;  Szenthe, Borbala;  Mucsi, Zoltan;  Graf, Laszlo;  Perczel, Andras
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/07
Mapping enzyme-inhibitor interactions by multidimensional NMR of double-labeled peptides 会议论文
会议名称: 3rd International Peptide Symposium/28th European Peptide Symposium. 会议地点: Prague, CZECH REPUBLIC. 会议日期: SEP 05-10, 2004
作者:  Gaspari, Zoltan;  Szenthe, Borbala;  Graf, Laszlo;  Perczel, Andras
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/07