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| Systems-level genetic patterns underlying disseminated coccidioidomycosis in humans 项目
项目编号: 1R21AI152394-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2020-2022
负责人: LUSSIER, YVES A.
  收藏 | 浏览/下载：5/0 | 提交时间：2021/08/12
Acute Address adverse outcome African American Alleles Automobile Driving Biochemical Biological Biological Process Biology bone Brain Candidate Disease Gene Caring Case Study Categories causal variant Chronic Clinical clinical care Coccidioides Coccidioidomycosis Code cohort Communicable Diseases Complex Data Databases desert fever design Disease Disease susceptibility DNA Emerging Communicable Diseases Equilibrium Exogenous Factors exome exome sequencing experience Filipino flu Foundations fungus Gene Expression Gene Mutation Genes Genetic genetic architecture Genetic Heterogeneity Genetic Predisposition to Disease genetic risk factor Genetic Variation genome-wide genome-wide analysis Genotype genotyped patients Guidelines Haplotypes Heterogeneity high risk HLA Antigens Human Human Genetics human leukocyte antigen testing IFNGR1 gene IL12RB1 gene Immune Immune response Immune system Immunocompetent Immunogenetics Immunological Models Immunosuppression Infection Inhalation insight Knowledge Life Lung Medical Modeling Molecular Mutation Mycoses National Institute of Allergy and Infectious Disease novel Organ Participant pathogen pathogen exposure Pathogenesis pathogenic fungus Pathology Pathway Analysis Pathway interactions Patients Pattern Phenotype Play Pneumonia Positioning Attribute Predisposition Proteins Quantitative Trait Loci rare variant Recommendation recruit Resistance Resources response Risk risk variant Role Sample Size Sampling Studies Signal Transduction Skin Soil STAT1 gene STAT3 gene Stimulus Symptoms System Systems Analysis Testing Therapeutic Time Variant whole genome |
| Understanding the natural Coccidioides bioaerosol in time and space and its relationship to disease 项目
项目编号: 1R21AI149660-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2020-2022
负责人: ENGELTHALER, DAVID M
收藏 | 浏览/下载：6/0 | 提交时间：2021/08/12
Address Aerosols Affect Air air filter air sampling Animals Area beta diversity Biological Assay Canis familiaris Climate climate change Coccidioides Coccidioidomycosis Collection Communities Community Health Data desert fever Detection Development Disease disease natural history disorder risk DNA Dust Ecology Environment Environmental Monitoring Environmental Risk Factor Environmental Wind epidemiologic data Epidemiology Event exposed human population Exposure to Fungal DNA Fungal Spores fungus Genomics Health Health Care Costs healthcare community Human Human Activities Humidity Incidence Infection Inhalation Knowledge knowledge base Locales Location Meteorology metropolitan microbiome analysis Modeling Monitor Morbidity - disease rate Movement Multivariate Analysis mycobiome Nature novel strategies Outcome Particulate Matter pathogen pathogenic fungus Pattern Population Precipitation predictive modeling Prevalence process optimization prospective Public Health Recreation Research Research Personnel Risk Risk Factors risk mitigation Schools severe weather Site Soil Source Southwestern United States Spatial Distribution suburb System Temperature The science of Mycology Time Veterinarians Weather whole genome Work Workplace |
| Project 1 - Environmental Project 1 - EP1 - Immobilization of U, As, and Co-occurring Metals in Mine Wastes 项目
项目编号: 5P42ES025589-04. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: CERRATO, JOSE MANUEL
收藏 | 浏览/下载：4/0 | 提交时间：2021/08/12
Address Adsorption Aerobic Affect Amendment aqueous Basic Science bioaccumulation Biological Carbonates Characteristics Chemicals Chemistry Climate Climate Controls Collaborations Communities Complement contaminated drinking water cultural values Custom Decision Making Desert Climate Development Ecology Engineering Environment Environmental Engineering technology Environmental Microbiology experience experimental study Exposure to Exudate Geographic Factor Goals Hazardous Substances Hazardous Waste Sites Health Home environment Human IGFBP2 gene Immobilization In Vitro Individual Ingestion innovation inorganic phosphate interfacial Intervention iron oxide Knowledge Laboratories Ligands mathematical model Measures member metagenome Metal exposure metal poisoning Metals Methods microbiome microbiome alteration microorganism Microscopy migration Minerals Mining Modeling Molecular Native Americans Navajo New Mexico next generation sequencing Outcomes Research Oxides Pattern Phase Pilot Projects Plant Roots Plants Play Population Precipitation prevent Process programs Pueblo Race Rain Reaction remediation Research Resources Risk Risk Reduction Role Sampling Science Scientist Seasons Site Soil Source Spectrum Analysis Superfund Surface System Techniques Testing tool Toxic effect toxic metal tribal community tribal lands Tribes Underserved Population Universities uptake Uranium wasting Water water flow |
| Project 2 - Macrophage regulation of fibrosis and scarring during tissue regeneration 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: GODWIN, JAMES W
收藏 | 浏览/下载：5/0 | 提交时间：2021/08/12
Address Adult Aging Animal Model Antigens Biological Assay Biological Models Brain Carbohydrates Cell Proliferation cell type Cells cellular targeting Cessation of life Cicatrix Comparative Biology Complex crosslink Development Disease Enzymes Epithelial Epithelial Cells Epithelium Exposure to Extracellular Matrix Fibroblasts Fibrosis Gene Expression Gene Expression Profile Genes Goals healing Healthcare Heart Human human tissue Immune Infection Infiltration Injury Innate Immune System innovation insight Label Laboratories Leukocytes limb amputation limb regeneration Limb structure Liver Lung macrophage Mammals Measures Mediating Mesenchymal Methods Modernization Molecular Myofibroblast Natural regeneration novel Operative Surgical Procedures Organ overexpression Patients Pattern Pharmacology Phenotype Play prevent Process progenitor programs Protein-Lysine 6-Oxidase Proteins PTPRC gene Recovery of Function regenerative regenerative therapy Regulation repaired RNA Interference Role Salamander Signal Pathway Signal Transduction Site Source Spinal Cord Stem cells Surface Testing therapy development Time time use tissue regeneration tissue repair Tissues tool transcriptome sequencing transdifferentiation Traumatic injury wound Wound Healing |
| Project 3 - Defining the role of ribosome protein composition in regulating the selective translation of pro-longevity genes 项目
项目编号: 5P20GM104318-08. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-
负责人: ROLLINS, JAROD ALTON
收藏 | 浏览/下载：3/0 | 提交时间：2021/08/12
Address Adult Affect Age age related Aging aging gene Animal Model Animals Biology of Aging Caenorhabditis elegans Caloric Restriction Cardiovascular Diseases Chronic Comparative Biology Cost of Illness CRISPR/Cas technology Data Databases Development differential expression Disease Drosophila genus Exposure to Gene Expression Genes Genetic genetic manipulation Genetic Models Genetic Transcription Genetic Translation Genome engineering Goals Health Health Expenditures healthy aging High-Throughput RNA Sequencing Human innovation insight Invertebrates knock-down Life Longevity longevity gene Malignant Neoplasms Mass Spectrum Analysis Mediating Messenger RNA middle age Molecular Molecular Machines mRNA sequencing Mus Natural regeneration Nerve Degeneration novel overexpression Pathway interactions Pharmacologic Substance Polyribosomes polysome profiling prevent Process Proteins Proteomics Ribosomal Proteins Ribosomes Risk Factors RNA Interference Role stressor Testing therapy development Time tissue repair Transcript transcriptomics Translating Translations Vertebrates Yeasts |
| Clinical Markers and Monitoring for Post-9-11 Deployment Lung Diseases 项目
项目编号: 1IK2CX001779-01A1. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-2024
负责人: KREFFT, SILPA DHOMA
收藏 | 浏览/下载：0/0 | 提交时间：2021/08/12 |
| Project 1 - Environmental Project 1 - EP1 - Immobilization of U, As, and Co-occurring Metals in Mine Wastes 项目
项目编号: 5P42ES025589-02. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2018-
负责人: CERRATO, JOSE MANUEL
收藏 | 浏览/下载：3/0 | 提交时间：2021/08/12
Address Adsorption Aerobic Affect Amendment aqueous Basic Science bioaccumulation Biological Carbonates Characteristics Chemicals Chemistry Climate Climate Controls Collaborations Communities Complement contaminated drinking water cultural values Custom Decision Making Desert Climate Development Ecology Engineering Environment Environmental Engineering technology Environmental Microbiology experience experimental study Exposure to Exudate Geographic Factor Goals Hazardous Substances Hazardous Waste Sites Health Home environment Human IGFBP2 gene Immobilization In Vitro Individual Ingestion innovation inorganic phosphate interfacial Intervention Knowledge Laboratories Ligands mathematical model Measures member metagenome Metal exposure metal poisoning Metals Methods microbiome microbiome alteration microorganism Microscopy migration Minerals Mining Modeling Molecular Native Americans Navajo New Mexico next generation sequencing Outcomes Research Oxides Pattern Phase Pilot Projects Plant Roots Plants Play Population Precipitation prevent Process programs Pueblo Race Rain Reaction remediation Research Resources Risk Risk Reduction Role Sampling Science Scientist Seasons Site Soil Source Spectrum Analysis Superfund Surface System Techniques Testing tool Toxic effect toxic metal tribal community tribal lands Tribes Underserved Population Universities uptake Uranium wasting Water water flow |
| Role of NRF2 in the Pulmonary Response to Inhaled Mine Tailing Dust 项目
项目编号: 5P42ES004940-29. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2018-
负责人: ZHANG, DONNA D
收藏 | 浏览/下载：6/0 | 提交时间：2021/08/12
Adverse effects Affect airway epithelium Alveolar Arsenic Autophagocytosis base Binding Biological Assay Biological Markers Bronchiectasis Butter Carcinogens Cells Chemopreventive Agent Chronic Chronic Bronchitis Chronic Obstructive Airway Disease CRISPR/Cas technology Cytosol Data defense response Degradation Pathway Desert Climate Development Diet Dietary Supplementation Disease disease registry Dose Dust Epithelial Epithelial Cells epithelial to mesenchymal transition Epithelium Erythroid exposure route Exposure to Fibrosis Functional disorder Gene Expression Gene Targeting Generations Goals Health high risk In Vitro in vivo Infiltration Inflammation Inflammatory Ingestion Inhalation Injury Intervention Iron Lung Lung diseases Lung Inflammation lung injury Maintenance Malignant Neoplasms Measures Mediating Metal exposure Metals Mining mitochondrial dysfunction Molecular Mus mutant Non-Malignant Nuclear Occupational Health Organ Organelles Outcome Oxidative Stress particle Particulate Pathway interactions Poison Population Intervention Populations at Risk Preventive Preventive treatment prophylactic protein aggregate Proteins Public Health Pulmonary Emphysema remediation Reporting Research Respiratory physiology response Risk Role Severities Side Site Soil Structure Sulforaphane superfund site Supplementation Tail Testing Therapeutic Tight Junctions Tissues Toxic effect transcription factor transcriptomics wasting |
| Data to Action: A Secondary School-based Citizen Science Project to Address Arsenic Contamination of Well Water 项目
项目编号: 1R25GM129796-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2018-2023
负责人: DISNEY, JANE E
收藏 | 浏览/下载：1/0 | 提交时间：2021/08/12
Clinical Research Foodborne Illness Pediatric |
| Data to Action: A Secondary School-based Citizen Science Project to Address Arsenic Contamination of Well Water 项目
项目编号: 3R25GM129796-02S1. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2018-2023
负责人: DISNEY, JANE ELIZABETH
收藏 | 浏览/下载：10/0 | 提交时间：2021/08/12
Address Arsenic base Biomedical Research career Centers for Disease Control and Prevention (U.S.) citizen science Committee Members Communication Communities Competence Computer software Data Data Analyses data portal data sharing drinking water Educational Curriculum Educational workshop Environmental Health Environmental Monitoring experience Future Teacher Generations Goals ground water hazard Health health data Home environment improved innovation Institutes Institution interest Knowledge Lead Learning Link literacy Maine Mathematics Measurable Medicine meetings Mentors Modeling Monitor Motivation Neighborhood Health Center New Hampshire novel Privatization Process programs Public Health recruit remediation Resources role model Rural School Teachers Schools Science science teacher Science, Technology, Engineering and Mathematics Education Scientific Inquiry Scientist Secondary Schools Services skills STEM career Students support network teacher teacher mentor Teacher Professional Development tool Training Translating water sampling water testing web site well water Work |
