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Immunogenomic characterization in gastric cancer identifies microenvironmental and immunotherapeutically relevant gene signatures 期刊论文
发表期刊: IMMUNITY INFLAMMATION AND DISEASE. 出版年: 2022
作者:  Han, Xiao;  Lu, Heyue;  Tang, Xiaojun;  Zhao, Yao;  Liu, Hongxue
收藏  |  浏览/下载：25/0  |  提交时间：2021/11/19
immune checkpoint  immunogenomic phenotype  immunotherapy  prognosis  tumor microenvironment  
Histologic-Based Tumor-Associated Immune Cells Status in Clear Cell Renal Cell Carcinoma Correlates with Gene Signatures Related to Cancer Immunity and Clinical Outcomes 期刊论文
发表期刊: BIOMEDICINES. 出版年: 2022, 卷号: 10, 期号: 2
作者:  Ohe, Chisato;  Yoshida, Takashi;  Ikeda, Junichi;  Tsuzuki, Toyonori;  Ohashi, Riuko;  Ohsugi, Haruyuki;  Atsumi, Naho;  Yamaka, Ryosuke;  Saito, Ryoichi;  Yasukochi, Yoshiki;  Higasa, Koichiro;  Kinoshita, Hidefumi;  Tsuta, Koji
收藏  |  浏览/下载：14/0  |  提交时间：2022/03/17
clear cell renal cell carcinoma  immunophenotype  immunohistochemistry  gene expression signatures  cancer immunity  clinical outcome  
Anti-VEGF antibody triggers the effect of anti-PD-L1 antibody in PD-L1(low) and immune desert-like mouse tumors 期刊论文
发表期刊: ONCOLOGY REPORTS. 出版年: 2022, 卷号: 47, 期号: 2
作者:  Ishikura, Nobuyuki;  Sugimoto, Masamichi;  Yorozu, Keigo;  Kurasawa, Mitsue;  Kondoh, Osamu
收藏  |  浏览/下载：5/0  |  提交时间：2022/02/12
anti-programmed death-ligand 1  anti-vascular endothelial growth factor  atezolizumab  bevacizumab  C-X-C motif chemokine receptor 3 ligands  immune desert  
Fighting in a wasteland: deleterious metabolites and antitumor immunity 期刊论文
发表期刊: JOURNAL OF CLINICAL INVESTIGATION. 出版年: 2022, 卷号: 132, 期号: 2
作者:  Watson, McLane J.;  Delgoffe, Greg M.
收藏  |  浏览/下载：7/0  |  提交时间：2022/03/17
Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy 期刊论文
发表期刊: CANCER DISCOVERY. 出版年: 2022, 卷号: 12, 期号: 1
作者:  Herrera, Fernanda G.;  Ronet, Catherine;  de Olza, Maria Ochoa;  Barras, David;  Crespo, Isaac;  Andreatta, Massimo;  Corria-Osorio, Jesus;  Spill, Aodrenn;  Benedetti, Fabrizio;  Genolet, Raphael;  Orcurto, Angela;  Imbimbo, Martina;  Ghisoni, Eleonora;  Rodrigo, Blanca Navarro;  Berthold, Dominik R.;  Sarivalasis, Apostolos;  Zaman, Khalil;  Duran, Rafael;  Dromain, Clarisse;  Prior, John;  Schaefer, Niklaus;  Bourhis, Jean;  Dimopoulou, Georgia;  Tsourti, Zoi;  Messemaker, Marius;  Smith, Thomas;  Warren, Sarah E.;  Foukas, Periklis;  Rusakiewicz, Sylvie;  Pittet, Mikael J.;  Zimmermann, Stefan;  Sempoux, Christine;  Dafni, Urania;  Harari, Alexandre;  Kandalaft, Lana E.;  Carmona, Santiago J.;  Laniti, Denarda Dangaj;  Irving, Melita;  Coukos, George
收藏  |  浏览/下载：8/0  |  提交时间：2022/03/17
Cancer-associated fibroblasts: Key players in shaping the tumor immune microenvironment 期刊论文
发表期刊: IMMUNOLOGICAL REVIEWS. 出版年: 2021
作者:  Desbois, Melanie;  Wang, Yulei
收藏  |  浏览/下载：21/0  |  提交时间：2021/07/30
cancer-associated fibroblast  immune-excluded  immune-desert  immune-infiltrated  TGF beta  tumor-immune phenotype  
Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination 期刊论文
发表期刊: NATURE MEDICINE. 出版年: 2021, 卷号: 27, 期号: 1, 页码: 152-+
作者:  Yu, Jiali;  Green, Michael D.;  Li, Shasha;  Sun, Yilun;  Journey, Sara N.;  Choi, Jae Eun;  Rizvi, Syed Monem;  Qin, Angel;  Waninger, Jessica J.;  Lang, Xueting;  Chopra, Zoey;  El Naqa, Issam;  Zhou, Jiajia;  Bian, Yingjie;  Jiang, Long;  Tezel, Alangoya;  Skvarce, Jeremy;  Achar, Rohan K.;  Sitto, Merna;  Rosen, Benjamin S.;  Su, Fengyun;  Narayanan, Sathiya P.;  Cao, Xuhong;  Wei, Shuang;  Szeliga, Wojciech;  Vatan, Linda;  Mayo, Charles;  Morgan, Meredith A.;  Schonewolf, Caitlin A.;  Cuneo, Kyle;  Kryczek, Ilona;  Ma, Vincent T.;  Lao, Christopher D.;  Lawrence, Theodore S.;  Ramnath, Nithya;  Wen, Fei;  Chinnaiyan, Arul M.;  Cieslik, Marcin;  Alva, Ajjai;  Zou, Weiping
收藏  |  浏览/下载：22/0  |  提交时间：2021/03/08
Ubiquitin Modification Patterns of Clear Cell Renal Cell Carcinoma and the Ubiquitin Score to Aid Immunotherapy and Targeted Therapy 期刊论文
发表期刊: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 出版年: 2021, 卷号: 9
作者:  Zhou, Peng;  Lu, Yuchao;  Xun, Yang;  Xu, Jinzhou;  Liu, Chenqian;  Xia, Qidong;  Lu, Junlin;  Wang, Shaogang;  Hu, Jia
收藏  |  浏览/下载：4/0  |  提交时间：2021/07/30
ubiquitin code  unsupervised consensus clustering  clear-cell renal-cell carcinoma  immune signature  immune checkpoint blockade  targeted therapy  
Tumor Immunometabolism Characterization in Ovarian Cancer With Prognostic and Therapeutic Implications 期刊论文
发表期刊: FRONTIERS IN ONCOLOGY. 出版年: 2021, 卷号: 11
作者:  Yang, Miner;  Chen, Gaowen;  Gao, Kunjie;  Wang, Yifeng
收藏  |  浏览/下载：9/0  |  提交时间：2021/07/30
ovarian cancer  metabolism reprogramming  epinephrine biosynthesis  major histocompatibility complex  immune microenvironment  
Combine and conquer: manganese synergizing anti-TGF-beta/PD-L1 bispecific antibody YM101 to overcome immunotherapy resistance in non-inflamed cancers 期刊论文
发表期刊: JOURNAL OF HEMATOLOGY & ONCOLOGY. 出版年: 2021, 卷号: 14, 期号: 1
作者:  Yi, Ming;  Niu, Mengke;  Zhang, Jing;  Li, Shiyu;  Zhu, Shuangli;  Yan, Yongxiang;  Li, Ning;  Zhou, Pengfei;  Chu, Qian;  Wu, Kongming
收藏  |  浏览/下载：24/0  |  提交时间：2021/11/19
The tumor microenvironment  Manganese  cGAS-STING  PD-L1  TGF-beta  Bispecific antibody  Cancer immunotherapy