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Antidiarrheal and Cardio-Depressant Effects of Himalaiella heteromalla (D.Don) Raab-Straube: In Vitro, In Vivo, and In Silico Studies 期刊论文
发表期刊: PLANTS-BASEL. 出版年: 2022, 卷号: 11, 期号: 1
作者:  Saqib, Fatima;  Usman, Faisal;  Malik, Shehneela;  Bano, Naheed;  Ur-Rahman, Najm;  Riaz, Muhammad;  Marc (Vlaic), Romina Alina;  Muresan, Crina Carmen
收藏  |  浏览/下载：7/0  |  提交时间：2022/03/17
antidiarrheal  calcium ion channel  cardio-depressant  Himalaiella heteromalla  
A Combined Morphological and Molecular Evolutionary Analysis of Karst-Environment Adaptation for the Genus Urophysa (Ranunculaceae) 期刊论文
发表期刊: FRONTIERS IN PLANT SCIENCE. 出版年: 2021, 卷号: 12
作者:  Xie, Deng-Feng;  Cheng, Rui-Yu;  Fu, Xiao;  Zhang, Xiang-Yi;  Price, Megan;  Lan, Yan-Ling;  Wang, Chang-Bao;  He, Xing-Jin
收藏  |  浏览/下载：16/0  |  提交时间：2021/07/30
adaptive evolution  positive selection  transcriptome  Urophysa  karst environment  
Short QT syndrome: The current evidences of diagnosis and management 期刊论文
发表期刊: JOURNAL OF ARRHYTHMIA. 出版年: 2020, 卷号: 36, 期号: 6, 页码: 962-966
作者:  Dewi, Ivana P.;  Dharmadjati, Budi B.
收藏  |  浏览/下载：3/0  |  提交时间：2021/01/08
channelopathies  short QT syndrome  sudden cardiac death  
Optimization of Betulinic Acid analogs for T-type calcium channel inhibition for non-addictive relief of chronic pain 项目
项目编号: 1R41DA050364-01. 资助机构: US-NIH（美国国立卫生研究院）. 起止日期: 2019-2020
负责人:  KHANNA, RAJESH
收藏  |  浏览/下载：14/0  |  提交时间：2021/08/12
Absence of pain sensation  addiction  Affect  Afferent Neurons  American  Amitriptyline  Analgesics  analog  Antidepressive Agents  Arizona  Axon  Baclofen  base  Betulinic Acid  Biological Assay  biophysical properties  Calcium  Calcium Channel Blockers  Calcium Channel Inhibition  cancer pain  Cancer Patient  cancer survival  cancer therapy  Cell-Mediated Cytolysis  Cells  central sensitization  chemotherapeutic agent  chemotherapy  Chemotherapy-induced peripheral neuropathy  Chemotherapy-Oncologic Procedure  Chronic  chronic pain  chronic pain relief  chronic painful condition  Clinical  Clinical Trials  Complex  compliance behavior  Complication  counterscreen  Coupled  design  dorsal horn  Dose-Limiting  drug discovery  Drug Kinetics  Drug Targeting  duloxetine  Dysesthesias  effective therapy  Effectiveness  Esthesia  Feeling  Fiber  G-Protein-Coupled Receptors  Human  improved  In Vitro  in vivo  Indigenous  inhibitor/antagonist  Ion Channel  Laboratories  Lavandula  Lead  Malignant Neoplasms  Mediating  Mediator of activation protein  Medical  Medicinal Plants  meetings  Modeling  Muscle relaxants  Natural Products  Neuraxis  neuronal excitability  Neurons  Neuropathy  neurotoxic  neurotoxicity  neurotransmission  non-opioid analgesic  Norepinephrine  novel  novel therapeutics  Numbness  Opiate Addiction  Opioid  opioid misuse  Opioid Receptor  opioid sparing  opioid use  Oral  Paclitaxel  Pain  Pain management  pain model  pain relief  pain signal  painful neuropathy  Paresthesia  Pathogenesis  Pathway interactions  Peripheral  Peripheral Nerves  Peripheral Nervous System  Peripheral Nervous System Diseases  Pharmaceutical Preparations  Pharmacology  Pharmacotherapy  Phase  Plants  Platinum Compounds  preclinical study  Prevalence  Property  Protein Isoforms  Proteins  Quality of life  Rattus  Regimen  Regulation  reuptake  Role  Safety  screening  Sensory  sensory stimulus  Serotonin  Shock  side effect  Site  small molecule  somatosensory  Southwestern United States  Specificity  Spinal  Spinal Cord  Spinal Ganglia  Structure  success  Survival Rate  synaptic function  T-Type Calcium Channels  taxane  Testing  Tissues  Translating  Treatment Protocols  Universities  venlafaxine  Vinca Alkaloids  voltage  Work  
Domain II (S5-P) region in Lymnaea T-type calcium channels and its role in determining biophysical properties, ion selectivity and drug sensitivity 学位论文
出版年: 2014
作者:  Guan;Wendy
收藏  |  浏览/下载：0/0  |  提交时间：2019/11/29
Relationship between calcium decoding elements and plant abiotic-stress resistance 期刊论文
发表期刊: INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES. 出版年: 2008, 卷号: 4, 期号: 2, 页码: 116-125
作者:  Song, Wei-Yi;  Zhang, Zheng-Bin;  Shao, Hong-Bo;  Guo, Xiu-Lin;  Cao, Hong-Xing;  Zhao, Hong-Bin;  Fu, Zheng-Yan;  Hu, Xiao-Jun
收藏  |  浏览/下载：14/0  |  提交时间：2019/11/28
calcium signals decoding elements  stomatal closure  water use efficiency (WUE)  abiotic stress-resistance  
Multi-residue method for the determination of basic/neutral pharmaceuticals and illicit drugs in surface water by solid-phase extraction and ultra performance liquid chromatography-positive electrospray ionisation tandem mass spectrometry 期刊论文
发表期刊: JOURNAL OF CHROMATOGRAPHY A. 出版年: 2007, 卷号: 1161, 期号: 1-2, 页码: 132-145
作者:  Kasprzyk-Hordern, B.;  Dinsdale, R. M.;  Guwy, A. J.
收藏  |  浏览/下载：2/0  |  提交时间：2019/11/28
pharmaceuticals  illicit drugs  ultra performance liquid chromatography-tandem mass spectrometry  solid-phase extraction  water contamination  multi-residue method  ion suppression  
Simultaneous determination of psychoactive drugs and their metabolites in aqueous matrices by liquid chromatography mass spectrometry 期刊论文
发表期刊: ENVIRONMENTAL SCIENCE & TECHNOLOGY. 出版年: 2006, 卷号: 40, 期号: 23, 页码: 7321-7328
作者:  Hummel, Daniela;  Loeffler, Dirk;  Fink, Guido;  Ternes, Thomas A.
收藏  |  浏览/下载：2/0  |  提交时间：2019/11/28
Biomineralisation in reef-building corals: from molecular mechanisms to environmental control 期刊论文
发表期刊: COMPTES RENDUS PALEVOL. 出版年: 2004, 卷号: 3, 期号: 6-7, 页码: 453-467
作者:  Allemand, D;  Ferrier-Pages, C;  Furla, P;  Houlbreque, F;  Puverel, S;  Reynaud, S;  Tambutte, E;  Tambutte, S;  Zoccola, D
收藏  |  浏览/下载：13/0  |  提交时间：2019/11/28
coral  calcification  biomineralisation  ion carrier  calcium channel  Ca(2+)-ATPase  organic matrix  symbiosis  
Voltage-activated whole-cell K+ currents in lamina cells of the desert locust Schistocerca gregaria 期刊论文
发表期刊: JOURNAL OF EXPERIMENTAL BIOLOGY. 出版年: 1999, 卷号: 202, 期号: 14, 页码: 1939-1951
作者:  Benkenstein, C;  Schmidt, M;  Gewecke, M
收藏  |  浏览/下载：6/0  |  提交时间：2019/11/28
visual system  central nervous system  insect electrophysiology  ion channel  K+ current  Ca2+ current  locust  Schistocerca gregaria