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Anti-VEGF antibody triggers the effect of anti-PD-L1 antibody in PD-L1(low) and immune desert-like mouse tumors 期刊论文
发表期刊: ONCOLOGY REPORTS. 出版年: 2022, 卷号: 47, 期号: 2
作者:  Ishikura, Nobuyuki;  Sugimoto, Masamichi;  Yorozu, Keigo;  Kurasawa, Mitsue;  Kondoh, Osamu
收藏  |  浏览/下载：5/0  |  提交时间：2022/02/12
anti-programmed death-ligand 1  anti-vascular endothelial growth factor  atezolizumab  bevacizumab  C-X-C motif chemokine receptor 3 ligands  immune desert  
Tumor-immune landscape patterns before and after chemoradiation in resectable esophageal adenocarcinomas 期刊论文
发表期刊: JOURNAL OF PATHOLOGY. 出版年: 2022
作者:  Soeratram, Tanya T. D.;  Creemers, Aafke;  Meijer, Sybren L.;  de Boer, Onno J.;  Vos, Wim;  Hooijer, Gerrit K. J.;  van Berge Henegouwen, Mark, I;  Hulshof, Maarten C. C. M.;  Bergman, Jacques J. G. H. M.;  Lei, Ming;  Bijlsma, Maarten F.;  Ylstra, Bauke;  van Grieken, Nicole C. T.;  van Laarhoven, Hanneke W. M.
收藏  |  浏览/下载：11/0  |  提交时间：2022/02/12
esophageal adenocarcinoma  tumor-immune microenvironment  PD-L1  tumor-infiltrating lymphocytes  chemoradiotherapy  treatment response  digital image analysis  immunohistochemistry  biomarker  
Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy 期刊论文
发表期刊: CANCER DISCOVERY. 出版年: 2022, 卷号: 12, 期号: 1
作者:  Herrera, Fernanda G.;  Ronet, Catherine;  de Olza, Maria Ochoa;  Barras, David;  Crespo, Isaac;  Andreatta, Massimo;  Corria-Osorio, Jesus;  Spill, Aodrenn;  Benedetti, Fabrizio;  Genolet, Raphael;  Orcurto, Angela;  Imbimbo, Martina;  Ghisoni, Eleonora;  Rodrigo, Blanca Navarro;  Berthold, Dominik R.;  Sarivalasis, Apostolos;  Zaman, Khalil;  Duran, Rafael;  Dromain, Clarisse;  Prior, John;  Schaefer, Niklaus;  Bourhis, Jean;  Dimopoulou, Georgia;  Tsourti, Zoi;  Messemaker, Marius;  Smith, Thomas;  Warren, Sarah E.;  Foukas, Periklis;  Rusakiewicz, Sylvie;  Pittet, Mikael J.;  Zimmermann, Stefan;  Sempoux, Christine;  Dafni, Urania;  Harari, Alexandre;  Kandalaft, Lana E.;  Carmona, Santiago J.;  Laniti, Denarda Dangaj;  Irving, Melita;  Coukos, George
收藏  |  浏览/下载：9/0  |  提交时间：2022/03/17
Molecular Subtypes of Primary SCLC Tumors and Their Associations With Neuroendocrine and Therapeutic Markers 期刊论文
发表期刊: JOURNAL OF THORACIC ONCOLOGY. 出版年: 2022, 卷号: 17, 期号: 1
作者:  Qu, Song;  Fetsch, Patricia;  Thomas, Anish;  Pommier, Yves;  Schrump, David S.;  Miettinen, Markku M.;  Chen, Haobin
收藏  |  浏览/下载：31/0  |  提交时间：2022/03/17
CD8(+) T-cells  Intratumoral heterogeneity  MYC  L-MYC  SLFN11  Synaptophysin  
Mammary Tumor-Derived Transplants as Breast Cancer Models to Evaluate Tumor-Immune Interactions and Therapeutic Responses 期刊论文
发表期刊: CANCER RESEARCH. 出版年: 2022, 卷号: 82, 期号: 3, 页码: 365-376
作者:  Moore, Jade;  Ma, Lin;  Lazar, Ann A.;  Barcellos-Hoff, Mary Helen
收藏  |  浏览/下载：4/0  |  提交时间：2022/03/17
The Prognostic Value of FoxP3+Tumour-Infiltrating Lymphocytes in Rectal Cancer Depends on Immune Phenotypes Defined by CD8+Cytotoxic T Cell Density 期刊论文
发表期刊: FRONTIERS IN IMMUNOLOGY. 出版年: 2022, 卷号: 13
作者:  Schnellhardt, Soeren;  Hirneth, Johannes;  Buettner-Herold, Maike;  Daniel, Christoph;  Haderlein, Marlen;  Hartmann, Arndt;  Fietkau, Rainer;  Distel, Luitpold
收藏  |  浏览/下载：19/0  |  提交时间：2022/03/17
Foxp3  CD8  regulatory T cells  rectal cancer  tumour-infiltrating lymphocytes  TILs  immune phenotypes  prognosis  
Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination 期刊论文
发表期刊: NATURE MEDICINE. 出版年: 2021, 卷号: 27, 期号: 1, 页码: 152-+
作者:  Yu, Jiali;  Green, Michael D.;  Li, Shasha;  Sun, Yilun;  Journey, Sara N.;  Choi, Jae Eun;  Rizvi, Syed Monem;  Qin, Angel;  Waninger, Jessica J.;  Lang, Xueting;  Chopra, Zoey;  El Naqa, Issam;  Zhou, Jiajia;  Bian, Yingjie;  Jiang, Long;  Tezel, Alangoya;  Skvarce, Jeremy;  Achar, Rohan K.;  Sitto, Merna;  Rosen, Benjamin S.;  Su, Fengyun;  Narayanan, Sathiya P.;  Cao, Xuhong;  Wei, Shuang;  Szeliga, Wojciech;  Vatan, Linda;  Mayo, Charles;  Morgan, Meredith A.;  Schonewolf, Caitlin A.;  Cuneo, Kyle;  Kryczek, Ilona;  Ma, Vincent T.;  Lao, Christopher D.;  Lawrence, Theodore S.;  Ramnath, Nithya;  Wen, Fei;  Chinnaiyan, Arul M.;  Cieslik, Marcin;  Alva, Ajjai;  Zou, Weiping
收藏  |  浏览/下载：22/0  |  提交时间：2021/03/08
Liver metastases inhibit immunotherapy efficacy 期刊论文
发表期刊: NATURE MEDICINE. 出版年: 2021, 卷号: 27, 期号: 1, 页码: 25-27
作者:  Lindblad, Katherine E.;  Lujambio, Amaia
收藏  |  浏览/下载：0/0  |  提交时间：2021/03/08
Immune profiling and immunotherapeutic targets in pancreatic cancer 期刊论文
发表期刊: ANNALS OF TRANSLATIONAL MEDICINE. 出版年: 2021, 卷号: 9, 期号: 2
作者:  Lenzo, Felicia L.;  Kato, Shumei;  Pabla, Sarabjot;  DePietro, Paul;  Nesline, Mary K.;  Conroy, Jeffrey M.;  Burgher, Blake;  Glenn, Sean T.;  Kuvshinoff, Boris;  Kurzrock, Razelle;  Morrison, Carl
收藏  |  浏览/下载：3/0  |  提交时间：2021/07/30
Precision immunotherapy  PD-L1  immune suppression  immune activation  checkpoint inhibitors  
RIPK3 activation induces TRIM28 derepression in cancer cells and enhances the anti-tumor microenvironment 期刊论文
发表期刊: MOLECULAR CANCER. 出版年: 2021, 卷号: 20, 期号: 1
作者:  Park, Han-Hee;  Kim, Hwa-Ryeon;  Park, Sang-Yeong;  Hwang, Sung-Min;  Hong, Sun Mi;  Park, Sangwook;  Kang, Ho Chul;  Morgan, Michael J.;  Cha, Jong-Ho;  Lee, Dakeun;  Roe, Jae-Seok;  Kim, You-Sun
收藏  |  浏览/下载：2/0  |  提交时间：2021/11/19
RIPK3  TRIM28  NF-kappa B  Transcriptional regulator  Chromatin  Immunostimulatory cytokines